Marc Humbert Selected Research

Chemokines

6/2014	Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension.
6/2009	Inflammation, growth factors, and pulmonary vascular remodeling.
9/2008	Mediators involved in HIV-related pulmonary arterial hypertension.
3/2005	New chemokine targets for asthma therapy.
12/2003	The CX3C chemokine fractalkine in allergic asthma and rhinitis.
5/2002	CX(3)C chemokine fractalkine in pulmonary arterial hypertension.
2/2002	Chemokine RANTES in severe pulmonary arterial hypertension.

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Marc Humbert Research Topics

Disease

197	Pulmonary Arterial Hypertension 10/2024 - 01/2002
132	Pulmonary Hypertension 10/2024 - 03/2002
56	Asthma (Bronchial Asthma) 12/2023 - 12/2003
37	Hypoxia (Hypoxemia) 10/2024 - 12/2009
34	Familial Primary Pulmonary Hypertension 07/2021 - 02/2002
30	Inflammation (Inflammations) 09/2023 - 12/2003
25	Vascular Remodeling 09/2023 - 12/2005
17	Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary) 12/2022 - 03/2002
14	Systemic Scleroderma (Systemic Sclerosis) 03/2024 - 06/2007
14	Connective Tissue Diseases (Connective Tissue Disease) 03/2024 - 01/2004
12	Fibrosis (Cirrhosis) 04/2024 - 08/2002
12	Neoplasms (Cancer) 01/2022 - 07/2010
11	Heart Failure 12/2023 - 08/2002
11	Interstitial Lung Diseases (Interstitial Lung Disease) 10/2023 - 08/2011
9	Disease Progression 04/2024 - 05/2010
9	Infections 01/2020 - 01/2004
8	Chronic Obstructive Pulmonary Disease (COPD) 12/2022 - 02/2010
8	Hypertrophy 01/2021 - 09/2002
7	Hypertension (High Blood Pressure) 10/2023 - 01/2006
7	Congenital Heart Defects (Congenital Heart Defect) 10/2021 - 01/2004
7	Lung Diseases (Lung Disease) 01/2021 - 02/2008
6	Portal Hypertension 04/2024 - 01/2004
6	Rare Diseases (Rare Disease) 12/2022 - 01/2002
6	COVID-19 10/2022 - 01/2020
6	Right Ventricular Hypertrophy 01/2020 - 01/2013
6	Hyperplasia 08/2011 - 03/2002
5	Dyspnea (Shortness of Breath) 05/2024 - 06/2008
5	Sarcoidosis (Schaumann Disease) 01/2021 - 06/2012
5	Pulmonary Edema 10/2017 - 07/2008
5	HIV Infections (HIV Infection) 10/2013 - 12/2004
4	Mixed Connective Tissue Disease (MCTD) 10/2023 - 07/2006
4	Body Weight (Weight, Body) 04/2023 - 09/2014
4	Hemorrhage 02/2021 - 01/2010
4	Pleural Effusion (Pleural Effusions) 10/2020 - 03/2002
4	Allergic Rhinitis 05/2019 - 12/2003

Drug/Important Bio-Agent (IBA)

34	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 10/2004
32	MonocrotalineIBA 01/2023 - 12/2009
24	Epoprostenol (Prostacyclin)FDA LinkGeneric 12/2019 - 02/2002
16	CytokinesIBA 01/2023 - 02/2002
16	riociguatIBA 10/2022 - 07/2013
15	Vasodilator Agents (Vasodilators)IBA 08/2021 - 02/2002
14	Endothelin Receptor AntagonistsIBA 01/2023 - 12/2004
14	Omalizumab (Xolair)FDA Link 11/2022 - 01/2008
14	Bosentan (Tracleer)FDA Link 01/2021 - 12/2004
13	Biomarkers (Surrogate Marker)IBA 09/2023 - 10/2012
13	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 12/2022 - 06/2008
12	Monoclonal AntibodiesIBA 01/2021 - 01/2008
10	Dasatinib (BMS 354825)FDA Link 03/2024 - 05/2012
10	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2023 - 06/2002
10	Proteins (Proteins, Gene)FDA Link 04/2023 - 12/2005
10	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 02/2002
9	ProstaglandinsIBA 01/2022 - 09/2002
9	mepolizumabIBA 01/2022 - 07/2014
9	Immunoglobulin E (IgE)IBA 01/2021 - 08/2013
8	AntibodiesIBA 10/2023 - 01/2008
8	Oxygen (Dioxygen)IBA 04/2022 - 08/2002
7	pro-brain natriuretic peptide (1-76)IBA 10/2023 - 01/2007
7	Carbon MonoxideIBA 01/2021 - 01/2010
7	Sildenafil Citrate (Viagra)FDA Link 01/2018 - 01/2004
7	Serotonin (5 Hydroxytryptamine)IBA 02/2017 - 10/2002
7	ChemokinesIBA 06/2014 - 02/2002
6	Phosphodiesterase 5 InhibitorsIBA 01/2023 - 09/2009
6	Interleukin-6 (Interleukin 6)IBA 01/2022 - 02/2013
6	Soluble Guanylyl CyclaseIBA 02/2021 - 07/2013
6	SteroidsIBA 01/2021 - 02/2007
6	Type II Bone Morphogenetic Protein Receptors (Bone Morphogenetic Protein Receptor Type II)IBA 12/2019 - 01/2013
6	Endothelins (Endothelin)IBA 12/2014 - 12/2004
6	Transforming Growth Factor beta (TGF-beta)IBA 01/2014 - 01/2002
5	Imatinib Mesylate (Gleevec)FDA Link 01/2024 - 10/2012
5	Activins (Activin)IBA 11/2023 - 01/2021
5	AnticoagulantsIBA 11/2023 - 11/2016
5	LeptinIBA 09/2023 - 10/2012
5	ProteomeIBA 01/2023 - 10/2016
5	Appetite Depressants (Anorectics)IBA 12/2022 - 01/2004
5	Platelet-Derived Growth FactorIBA 01/2022 - 07/2008
5	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2021 - 09/2015
5	anti-IgE antibodiesIBA 01/2021 - 01/2008
5	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2020 - 09/2006
5	Endothelin-1 (Endothelin 1)IBA 01/2019 - 08/2005
5	Phosphotransferases (Kinase)IBA 01/2018 - 10/2012
4	SolventsIBA 07/2023 - 12/2015
4	Brain Natriuretic Peptide (Natrecor)FDA Link 04/2023 - 07/2013
4	ACE-011IBA 04/2023 - 01/2021
4	Semaxinib (SU5416)IBA 01/2023 - 01/2018
4	FenfluramineIBA 12/2022 - 06/2005
4	Messenger RNA (mRNA)IBA 11/2021 - 02/2002
4	GlucocorticoidsIBA 01/2020 - 02/2008
4	Tadalafil (Cialis)FDA Link 12/2019 - 09/2009
4	Tyrosine Kinase InhibitorsIBA 01/2018 - 06/2009
4	Interleukin-5 (Interleukin 5)IBA 01/2018 - 09/2013
4	activin receptor type II-A (activin A receptor, type II)IBA 01/2017 - 04/2010
4	Transcription Factors (Transcription Factor)IBA 11/2016 - 01/2013
4	InterferonsIBA 01/2016 - 02/2014

Therapy/Procedure

114	Therapeutics 01/2024 - 03/2002
20	Lung Transplantation 12/2022 - 09/2002
13	Endarterectomy (Thromboendarterectomy) 03/2022 - 09/2006
12	Transplantation 01/2024 - 03/2006
8	Drug Therapy (Chemotherapy) 07/2023 - 01/2015
7	Heart-Lung Transplantation 01/2024 - 10/2012
4	Liver Transplantation 01/2022 - 01/2017